A simple synthesis of pyrroles catalyzed by acidic resin under solvent-free condition

✍ Scribed by Shizhen Yuan; Zhen Li; Ling Xu

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2010
• Tongue: English
• Weight: 130 KB
• Volume: 47
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.300

✦ Synopsis

Abstract

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A simple and effective Paal‐Knorr condensation of 2, 5‐hexanedione with most amines has been carried out at room temperature under solvent‐free condition. The pyrroles were obtained in high yields and in short reaction times. J. Heterocyclic Chem., (2010).