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A simple synthesis of dl-chalcose

✍ Scribed by Danishefsky, Samuel; Kerwin, James F.


Book ID
120791182
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
279 KB
Volume
47
Category
Article
ISSN
0022-3263

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In the previous papers 1)2) concerning the synthesis of muscarines, we reported a partially stereospecific synthesis in which the hydroxyl group of a diacid (I) was introduced selectively in trans manner to the methyl group. Decarboxylation of I, however , proceeded non-stereoselectively giving a m

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7] a ) Satiafdctory elemental analyses were obtained for D -3 to 0-6 [Route The threo-dipropenylglycol DL-I, which is obtained by (a)] and I ) -/ L -~ [Route (b)]; b) due to difficulties in purification of such reductive dimerization of crotonaldehvde["l and simDle compounds and uncertainties in the