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A simple statistical field theory of heteropolymer collapse with application to protein folding

✍ Scribed by Joseph D. Bryngelson; Peter G. Wolynes

Publisher: Wiley (John Wiley & Sons)
Year: 1990
Tongue: English
Weight: 830 KB
Volume: 30
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360300117

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✦ Synopsis

A simple statistical extension of the Flory theory of excluded volume is developed, and applied to random heteropolymer collapse and a simple model of protein folding. Sequence heterogeneity is found to lead to new effects. The nucleation of protein folding is also briefly considered.

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