A simple solution to the oxazole problem in virginiamycin M

✍ Scribed by Richard D. Wood; Bruce Ganem

• Book ID: 104219882
• Publisher: Elsevier Science
• Year: 1983
• Tongue: French
• Weight: 97 KB
• Volume: 24
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)85905-5

✦ Synopsis

By first silylating at C5, 2-methyl-1,3-oxazole-4-carboxylic acid may readily be metallated and alkylated at the ring methyl group.