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A Simple Radioenzymatic Method to Measure Picogram Amounts of DOPA in Brain and Biological Fluids

✍ Scribed by A. Argiolas; G. L. Gessa


Book ID
111171532
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
210 KB
Volume
36
Category
Article
ISSN
0022-3042

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A simple, specific, radioenzymatic assay
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This report describes several modifications of the original radioenzymatic assay for serotonin (4) which increase the sensitivity of the assay IO-fold as well as enhance its reliability. Serotonin is converted to [3H]melatonin, in two steps. First, serotonin is acetylated to N-acetylserotonin by ace