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A simple process for the purification of arachidonic acid

โœ Scribed by E.J. Corey; Stephen W. Wright

Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
117 KB
Volume
25
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Pure arachidonic acid ( L ) and docosahexanoic acid ( 2 ) are available by a two-step purification method from commercial 50% acids with high efficiency.

Arachidonic acid ( J_ ) is an important starting material for biochemical studies and for the synthesis of eicosanoids such as leukotrienes and inhibitors of leukotriene biosynthesis. ' The high price of commercially available pure arachidonic acid has prompted the development of methods for the purification of impure (50%) but less expensive commercial material.

Previous methods2 have involved several laborious and expensive steps including chromatographic purification on silver nitrate impregnated silica gel.

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