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A simple procedure for producing oxygen-labelled inorganic phosphate from isotopically labelled water that optimizes yield based on the isotope

✍ Scribed by William J. Ray Jr.


Publisher
John Wiley and Sons
Year
1992
Tongue
French
Weight
107 KB
Volume
31
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

Phosphorus pentachloride can be treated with stoichiometric amounts of oxygen‐labelled water to produce 80–90 percent yields of labelled inorganic phosphate when the reaction is conducted in dioxane. Any phosphorus‐chlorine bonds remaining at the end of the reaction are eliminated by reaction with diethylamine prior to adding water.