A Simple Oxidation of γ- and δ-Lactones to Oxocarboxylic Acids by Buffered Sodium Hypochlorite.

✍ Scribed by Michele D'Ambrosio; Antonio Guerriero

• Publisher: John Wiley and Sons
• Year: 2003
• Weight: 15 KB
• Volume: 34
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.200322049

✦ Synopsis

A Simple Oxidation of γand δ-Lactones to Oxocarboxylic Acids by Buffered Sodium Hypochlorite. -γand δ-Lactones (I) can be transformed to the corresponding 4-or 5-oxocarboxylic acids by the reaction with commercial NaOCl. The reaction is not applicable to unsaturated lactones [cf. the formation of (IV) and (VI)]. -(