The pyrroloA C H T U N G T R E N N U N G [1,2-a]indole tricyclic ring structures are widely presented in a number of naturally occurring products and have attracted much attention due to the broad scope of their biological activities. [1] Representative examples are mitomycins, [1b] some of the most
✦ LIBER ✦
A simple one-pot 2-step N-1-alkylation of indoles with α-iminoketones toward the expeditious 3-step synthesis of N-1-quinoxaline-indoles
✍ Scribed by Martinez-Ariza, Guillermo; Ayaz, Muhammad; Hulme, Christopher
- Book ID
- 121265809
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 455 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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Evidence for a Stepwise Ionic Pathway in the Generation of Indole-2,3-quinodimethanes. -A strategy employing C-2 carbon substitution of (I) by NBS bromination is used for an effective synthesis of the lactone (IV). However, contrary to the previously reported analogues (V) compound (IV) is totally