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A Simple Model of Protein Folding Kinetics Based on Native Topology

โœ Scribed by Rollins, Geoffrey; Dill, Ken


Book ID
122179668
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
69 KB
Volume
102
Category
Article
ISSN
0006-3495

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Chaperonins are oligomeric proteins that help other proteins fold. They act, according to the "Anfinsen cage" or "box of infinite dilution" model, to provide private space, protected from aggregation, where a protein can fold. Recent evidence indicates, however, that proteins are often ejected from