Development of a novel method for predic
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Patrick Poulin; Frank-Peter Theil
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Article
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2009
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John Wiley and Sons
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English
โ 364 KB
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The parameters characterizing tissue distribution refer to the tissue/plasma partition coefficients (Kp), which can be used to derive volume of distribution at steady-state (V(ss)). The effort for predicting drug distribution in human has been further expanded to calculation methods using in vitro-b