A simple GC–MS technique for the analysis of vapor phase mainstream cigarette smoke
✍ Scribed by Ji-Zhou Dong; J. Neil Glass; Serban C. Moldoveanu
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 169 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1040-7685
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✦ Synopsis
This paper presents a simple gas chromatography᎐mass spectrometry Ž . GC᎐MS technique for the analysis of vapor phase mainstream cigarette smoke.
Ž . The analysis includes two parts: A separation and identification of as many as Ž . possible compounds in vapor phase smoke, and B quantitative analysis of a selected number of analytes. For achieving these objectives, the cigarettes are smoked using a Borgwaldt RM20rCS smoking machine using Federal Trade Ž . Ž . Commission FTC , International Organization for Standardization ISO , or other recommended conditions. The vapor phase smoke is separated from particulate phase smoke with a standard Cambridge pad. The vapor phase is collected in a gas Ž . bag, and then a precise volume 1 or 5 mL is injected in a GC᎐MS system for separation and analysis. About 90 compounds are separated and identified in vapor phase smoke. A quantitative procedure was developed for acetaldehyde, 1,3butadiene, acrolein, propionaldehyde, acetonitrile, acetone, isoprene, propionitrile, Ž . benzene, crotonaldehyde, hydrogen cyanide HCN , and styrene. Using appropriate standards, most of the other compounds identified in vapor phase smoke could also be quantitated. Excellent reproducibility is obtained using this technique, the results being in good agreement with previously reported work.