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A Simple Entry to Chiral Non-racemic 2-Piperazinone Derivatives.

✍ Scribed by Gian Piero Pollini; Nikla Baricordi; Simonetta Benetti; Carmela De Risi; Vinicio Zanirato


Book ID
101980496
Publisher
John Wiley and Sons
Year
2005
Weight
26 KB
Volume
36
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES


Diastereoselective synthesis of chiral n
✍ Jean-Philippe Ebran; Philippe Jubault; Xavier Pannecoucke; Jean-Charles Quirion πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 296 KB

Chiral a-amidophosphine boranes 7a-b can be diastereoselectively alkylated, using a phenylglycinol derivative as a chiral inducer, to furnish a-substituted a-amidophosphine boranes 8-12 with up to 99% diastereoisomeric excess. Selective reduction of the amidophosphine boranes afforded optically pure