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A Simple Correction for Multiple Testing for Single-Nucleotide Polymorphisms in Linkage Disequilibrium with Each Other

✍ Scribed by Dale R. Nyholt


Book ID
117854416
Publisher
American Society of Human Genetics
Year
2004
Tongue
English
Weight
203 KB
Volume
74
Category
Article
ISSN
0002-9297

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## Abstract Multiple testing is a challenging issue in genetic association studies using large numbers of single nucleotide polymorphism (SNP) markers, many of which exhibit linkage disequilibrium (LD). Failure to adjust for multiple testing appropriately may produce excessive false positives or ov