A simple and practical method for the synthesis of 2-amino-5,6-dihydro-5,7-diarylquinazolin-4-ols
✍ Scribed by S. Senguttuvan; Samuthira Nagarajan
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 62 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.229
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✦ Synopsis
Abstract
magnified image We report an efficient and new method of synthesis of 2‐amino‐5,6‐dihydro‐5,7‐diarylquinazolin‐4‐ols by the reaction of substituted cyclohexenones with guanidine hydrochloride in presence of NaOEt. The reactions are with 50–72% yield. All the synthesized compounds are characterized using IR, NMR and CHN analysis. J. Heterocyclic Chem., (2009).
📜 SIMILAR VOLUMES
## Abstract __N__‐(2‐Amino‐5,6,7,8‐tetrahydro‐6‐quinazolinyl)acetamide (**9**) and __N__‐(2,4‐diamino‐5,6,7,8‐tetrahydro‐6‐quinazolinyl)acetamide (**6**) were synthesized from __N__‐(4‐oxocyclohexyl)acetamide (**5**) as novel peptidomimetic building blocks. With similar purpose, __N__‐(6‐oxo‐5,6,7,
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