A SIMPLE AND EFFICIENT METHOD FOR THE EPOXIDATION OF α, β-UNSATURATED ALDEHYDES AND KETONES USING AQUEOUS HYDROGEN PEROXIDE-SODIUM ETHOXIDE
✍ Scribed by Patra, A.; Bandyopadhyay, M.; Ghorai, S. K.; Mal, D.
- Book ID
- 117992199
- Publisher
- Taylor and Francis Group
- Year
- 2003
- Tongue
- English
- Weight
- 293 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0030-4948
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## Abstract For Abstract see ChemInform Abstract in Full Text.
Aldehydes were converted into the corresponding nitriles by a homogeneous reaction with ammonia and aqueous hydrogen peroxide in the presence of copper salts or complexes under mild conditions.
Aryl-substituted epoxides undergo smooth rearrangement in the presence of 0.01-0.1 mol% Bi(OTf) 3 •xH 2 O. The rearrangement is regioselective with aryl-substituted epoxides, and products arise from cleavage of the benzylic C O bond. The highly catalytic nature of this method coupled with the fact t