A simple and efficient hydrolyzing method for tetrahydropyranyl ethers

✍ Scribed by Adam Shih-Yuan Lee; Feng-Yih Su; Yuan-Cheng Liao

• Book ID: 104260563
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 155 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)02602-1

✦ Synopsis

A series of tetrahydropyranyl ethers are hydrolyzed to the corresponding alcohols in a CBr4 / CH3OH (5% / 5mL) reaction system under refluxing. This method also enables to deprotect other functionalities such as acetals and ketals.