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A simple and efficient approach to the synthesis of β-N-methylamino-l-alanine (BMAA)

✍ Scribed by Arévalo-García, Enzo B.; Colmenares Q., Juan Carlos


Book ID
121724028
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
413 KB
Volume
55
Category
Article
ISSN
0040-4039

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Effects of L-β-N-methylamino-L-alanine (
✍ Z. Rakonczay; Y. Matsuoka; Dr. E. Giacobini 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 577 KB

Neurotoxic properties of L-p-methylamino-alanine (L-BMAA) after chronic intracerebroventricular (i.c.v.) (500 pgiday) administration up to 60 days were investigated in the cerebral cortex of the rat. At day 16, there was a significant decrease in acetylcholinesterase (AChE) activity, 3H-QNB binding,