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A simple and convenient route to 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines

✍ Scribed by Elena L Gaidarova; Anatoly A Borisenko; Taras I Chumakov; Andrey V Mel'nikov; Ivan S Orlov; Galina V Grishina

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 199 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01662-1

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✦ Synopsis

A simple and convenient synthetic approach to the new series of 1,2,3,4,5,6,7,8octahydro-l,6-naphthyridines la-j has been developed. This was achieved via a one-pot process combining metalated 4-piperidinonimine alkylation and intramolecular eyclization.

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