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A Simple Algorithm for Designing Group Sequential Clinical Trials

✍ Scribed by David A. Schoenfeld

Book ID
110724958
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
337 KB
Volume
57
Category
Article
ISSN
0006-341X

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The theory underlying sequential clinical trials is now well developed, and the methodology is increasingly being implemented in practice, both by the pharmaceutical industry and in the public sector. The consequences of conducting interim analyses for frequentist interpretations of data are now wel