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A short total synthesis of sulfobacin A

✍ Scribed by Olivier Labeeuw; Phannarath Phansavath; Jean-Pierre Genêt

Book ID: 104254204
Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 104 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01600-9

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✦ Synopsis

A total synthesis of the von Willebrand factor receptor antagonist sulfobacin A is described. Key steps for this short route to sulfobacin A include ruthenium-catalyzed asymmetric hydrogenation and diastereoselective electrophilic amination for the construction of the three stereogenic centers.

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