A short synthesis of 5,7-bis(dialkylamino)-2-methyl- 8 -hydroxyquinolines
✍ Scribed by George B. Okide
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2001
- Tongue
- English
- Weight
- 21 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
The bromine atoms of the title compound were replaced by the requisite amino compound to afford the desired derivatives in high yields. Thus, six target compounds viz‐ bis(diethylamino)‐, bis(dibutylamino)‐, bis(dicyclohexylamino)‐, dipyrrolidino‐, dipiperidino‐, and dipiperazino‐derivatives were obtained and characterized by spectral and elemental analyses.
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The synthesis of spiroketals from nitro ketones is described. Racemic __trans__‐2‐Methyl‐1,7‐dioxaspiro[5.5]undecane (1a), and 2,8‐dimethyl‐1,7‐dioxaspiro[5.5]undecane (1b) are synthesized as a mixture of __trans__, __trans__ and __trans__, __cis__ isomers in a ratio of 6.5:3.5 (separab