## Abstract __dl__βPumiliotoxinβC **(4)** was synthesized in a practical manner from __trans__β4βhexenal **(9)**. The key step **14** β **15** (__Scheme 3__) involves an intramolecular __Diels__β__Alder__ reaction giving mainly the __cis__βfused indanols **15a**, which were converted to the __cis__
β¦ LIBER β¦
A short stereospecific total synthesis of dl-pumiliotoxin C
β Scribed by Larry E. Overman; Peter J. Jessup
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 228 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Pumiliotoxin C (Q is one of a large group of structurally related toxins which have been isolated from shin extracts of the colorful Central American poison arrow frog Dendrobates pu milio 2, 3, 4, 5c . Synthetic investigations in several laboratories culminated in 1975 in three total syniheses of this unusual cis-decahydroquinoline alkaloid.
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