A short, simple and general approach for the synthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methylamino pyrrolidine
β Scribed by A.Ravi Kumar; J.Santhosh Reddy; B.Venkateswara Rao
- Book ID
- 104253999
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 169 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
N-Substituted (3S,4S)-and (3R,4R)-pyrrolidine-3,4-diols 9 and 10, respectively, were derived from ()-land (Γ)-d-tartaric acid, respectively. Compounds 9k, 9l, and 9m with the N-substituents, BnNH(CH 2 ) 2 , 4-PhC 6 H 4 CH 2 NH(CH 2 ) 2 and 4-ClC 6 H 4 CH 2 NH(CH 2 ) 2 , respectively, showed modest i
The synthesis of 46 derivatives of (2R,3R,4S)-2-(aminomethyl)pyrrolidine-3,4-diol is reported (Scheme 1 and Fig. 3), and their inhibitory activities toward a-mannosidases from jack bean (B) and almonds (A) are evaluated (Table ). The most-potent inhibitors are (2R,3R,4S)-2-{[([1,1'-biphenyl]-4-ylmet