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A short route to nucleoside diphosphate activated d- and l-hexoses

✍ Scribed by Christiane Ernst; Werner Klaffke

Book ID
104230423
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
63 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

Leloir transferases utilise nucleoside diphosphate sugars, which are notoriously difficult to synthesise and handle. Starting off from D-or L-configurated glycals, a facile synthesis of nucleotide sugars by epoxidation and direct coupling with uridine diphosphate is described.

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