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A short parameter-fitting routine for compartmental models

✍ Scribed by Henry A. Feldman

Publisher
Elsevier Science
Year
1977
Weight
497 KB
Volume
7
Category
Article
ISSN
0010-468X

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✦ Synopsis

We have developed a program of 298 FORTRAN statements which obtains the inter-pool exchange rates and other parameters of a compartmental system, working directly from the time course of tracer activity after a bolus injection. The fitting problemdata and model -is specified by the user in a natural syntactic style. The program calculates least-squares estimates, confidence limits and intercorrelation estimates for the fitted parameters. Its small size and conceptual simplicity make the program a powerful practical tool for analyzing tracer studies.

Compartmental analysis

Curve-fitting Tracer methods Kinetics

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