## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A Short, Facile Synthesis of 5-Substituted 3-Amino-1H-pyrrole-2-carboxylates
β Scribed by Chen, Ning; Lu, Yuelie; Gadamasetti, Kumar; Hurt, Clarence R.; Norman, Mark H.; Fotsch, Christopher
- Book ID
- 111901623
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 79 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3263
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## Abstract Ethyl 2β(chloromethyl)β2βhydroxyβ2__H__βchromeneβ3βcarboxylates **2a**β**2j** have been synthesized by reaction of substituted salicylaldehydes with ethyl 4βchloroβ3βoxobutanoate, in the presence of piperidine in CH~2~Cl~2~ at room temperature, in good yields.
A new synthesis of a series of 3-amino-1H-quinazoline-2,4-diones is described. The 1H-quinazoline-2,4dione 10 was made starting with fluorobenzoic acid in three high yielding steps. The key step of this synthesis involved the generation of the dianion of urea 7 and the subsequent intramolecular nucl