A Short Asymmetric Synthesis of the Benzopyrano[3,4- c ]pyrrolidine Core via an Organocatalytic Domino Oxa-Michael/Michael Reaction
โ Scribed by Wang, Chuan; Yang, Xuena; Raabe, Gerhard; Enders, Dieter
- Book ID
- 120867595
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 283 KB
- Volume
- 354
- Category
- Article
- ISSN
- 1615-4150
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๐ SIMILAR VOLUMES
Organocatalytic domino oxa-Michael-Michael-Michael-aldol condensation of 2-((E)-2-nitrovinyl)phenol and 2 equiv of a,b-unsaturated aldehydes (e.g., cinnamaldehyde) provided tetrahydro-6Hbenzo[c]chromenes in high diastereoselectivity and high enantioselectivity (>99% ee). Structure of the adduct 4a w
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