✦ LIBER ✦

A short and facile synthetic route to prenylated flavones. Cyclodehydrogenation of prenylated 2′-hydroxychalcones by a hypervalent iodine reagent

✍ Scribed by Katalin Gula´csi; Gyo¨rgy Litkei; Sa´ndor Antus; Tama´s E. Gunda

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 443 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(98)00853-9

No coin nor oath required. For personal study only.

✦ Synopsis

The first synthesis of the prenylated flavones kanzonoI-D (1), -E (3) and yinyanghuo-C (4) was accomplished by cyclodehydrogenation of the appropriately substituted 2'-hydroxychalcones 16, 14 and 11, respectively, in presence of phenyliodine(III) diacetate (PIDA) / potassium hydroxide m methanol. The synthesis of kanzonoI-B (13) was also achieved from the 2'-hydroxychalcone 12.

📜 SIMILAR VOLUMES

ChemInform Abstract: A Short and Facile

ChemInform Abstract: A Short and Facile Synthetic Route to Prenylated Flavones. Cyclodehydrogenation of Prenylated 2′-Hydroxychalcones by a Hypervalent Iodine Reagent.

✍ K. GULACSI; G. LITKEI; S. ANTUS; T. E. GUNDA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Cyclodehydrogenation of 2′-hydroxychalco

Cyclodehydrogenation of 2′-hydroxychalcones with hypervalent iodine reagent: A new synthesis of flavones

✍ Litkei, György ;Gulácsi, Katalin ;Antus, Sandor ;Blaskó, Gábor 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 465 KB 👁 1 views

## Abstract A new synthesis of chrysin (1) and luteolin (4) was accomplished by the cyclodehydrogenation of the appropriately substituted 2′‐hydroxychalcones 21 and 22 in the presence of iodosobenzene diacetate/potassium hydroxide in methanol. The scope and limitation of this transformation is disc

Facile and Efficient Synthesis of Lactol

Facile and Efficient Synthesis of Lactols by a Domino Reaction of 2,3-Epoxy Alcohols with a Hypervalent Iodine(III) Reagent and Its Application to the Synthesis of Lactones and the Asymmetric Synthesis of (+)-Tanikolide.

✍ Hiromichi Fujioka; Satoshi Matsuda; Mai Horai; Eri Fujii; Maiko Morishita; Natsu 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Facile and Efficient Synthesis of Lactol

✍ Hiromichi Fujioka; Satoshi Matsuda; Mai Horai; Eri Fujii; Maiko Morishita; Natsu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB 👁 2 views

## Abstract The domino reaction of 2,3‐epoxy‐1‐alcohol derivatives, namely tetrasubstituted 2,3‐epoxy‐1‐alcohols and 2‐ or 3‐alkyl trisubstituted 2,3‐epoxy‐1‐alcohols, with PhI(OCOCF~3~)~2~ in the presence of H~2~O is described in detail. In this reaction, several types of lactol derivatives can be