A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414)

✍ Scribed by Emmanuel Pinard; Serge Burner; Philippe Cueni; François Montavon; Daniel Zimmerli

• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 152 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.07.172

✦ Synopsis

A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4methyl pyrrolidin-2-one (L-687,414) is described.