Effects of serotonin 5-HT1A agonist in a
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William Bara-Jimenez; Francesco Bibbiani; Michael J. Morris; Tzvetelina Dimitrov
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Article
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2005
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John Wiley and Sons
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English
β 69 KB
## Abstract Intermittent stimulation of striatal dopaminergic receptors seems to contribute to motor dysfunction in advanced Parkinson's disease (PD). With severe dopaminergic denervation, exogenous levodopa is largely decarboxylated to dopamine in serotonergic terminals. If 5βHT1A autoreceptors re