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A Sequence-Independent Study of the Influence of Short Loop Lengths on the Stability and Topology of Intramolecular DNA G-Quadruplexes †

✍ Scribed by Bugaut, Anthony; Balasubramanian, Shankar


Book ID
121384124
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
250 KB
Volume
47
Category
Article
ISSN
0006-2960

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Spectroscopic and calorimetric melting studies of 28 DNA hairpins were performed. These hairpins form by intramolecular folding of 16 base self-complementary DNA oligomer sequences. Sequence design dictated that the hairpin structures have a six base pair duplex linked by a four base loop and that t