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A Separate Antibiotic-binding Site in Xanthosine-5'-phosphate Aminase: Inhibitor- and Substrate-binding Studies *

✍ Scribed by Fukuyama, T. T.; Moyed, H. S.


Book ID
127186929
Publisher
American Chemical Society
Year
1964
Tongue
English
Weight
682 KB
Volume
3
Category
Article
ISSN
0006-2960

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Role of Lys 558 and Lys 869 in substrate
✍ P. G. Wood; H. MΓΌller; M. Sovak; H. Passow πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 888 KB

The effect of mutation of either Lys 558 or Lys 869 or both on mouse erythroid band 3 protein (AE1)-mediated 36Cl- efflux and its inhibition by pyridoxal 5-phosphate (P5-P), DNDS and H2DIDS were studied. Regardless of the mutation, band 3 was always capable of executing Cl- self-exchange. P5-P (5 mM