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A sensitive human cell line based bioassay for megakaryocyte growth and development factor or thrombopoietin

✍ Scribed by Lisa A. Page; Robin Thorpe; Anthony R. Mire-Sluis


Book ID
115595864
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
64 KB
Volume
8
Category
Article
ISSN
1043-4666

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We have isolated a subline of the M-07 human megakaryoblastic leukemia cell line, designated M-07e, that requires either interleukin-3 (11-3) or granulocyte macrophage colony-stimulating factor (GM-CSF) for growth, even in the presence of fetal calf serum. This cell line will not grow long term in a