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A sensitive fluorometric assay for quantitatively measuring specific peptide binding to HLA class I and class II molecules

✍ Scribed by Tom H.M. Ottenhoff; Annemieke Geluk; Mireille Toebes; Willemien E. Benckhuijsen; Krista E. van Meijgaarden; Jan Wouter Drijfhout


Book ID
114051653
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
810 KB
Volume
200
Category
Article
ISSN
0022-1759

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A direct and sensitive biochemical assay to measure the interaction in solution between peptides and affinity-purified major histocompatibility complex (MHC) class I molecules has been generated. Specific binding reflecting the known class I restriction of cytotoxicT cell responses was obtained. Add