A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry
β Scribed by Jeroen J.M.A. Hendrikx; Michel J.X. Hillebrand; Bas Thijssen; Hilde Rosing; Alfred H. Schinkel; Jan H.M. Schellens; Jos H. Beijnen
- Book ID
- 116620540
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 541 KB
- Volume
- 879
- Category
- Article
- ISSN
- 1873-376X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A sensitive and specific LC-MS/MS assay for the determination of paclitaxel and its 3'p- and 6-alpha-hydroxy metabolites is presented. A 200 microL plasma aliquot was spiked with a 13C6-labeled paclitaxel internal standard and extracted with 1.0 mL tert-butylmethylether. Dried extracts were reconsti
## Abstract A simple, rapid, sensitive and specific liquid chromatography/electrospray ionization mass spectrometry method was developed and validated to quantify azithromycin in human plasma, using erythromycin as the internal standard (IS). A simple sample preparation method of protein precipitat
A simple, rapid, sensitive and specific liquid chromatography-tandem mass spectrometry method was developed and validated for quantification of hydrochlorothiazide (I), a common diuretic and anti-hypertensive agent. The analyte and internal standard, tamsulosin (II) were extracted by liquid-liquid e