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A sensitive and specific chemiluminescence method for estimating the ability of human granulocytes and monocytes to generate O2−

✍ Scribed by Akira Nishida; Hirokazu Kimura; Minoru Nakano; Toshio Goto

Book ID
115826499
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
367 KB
Volume
179
Category
Article
ISSN
0009-8981

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Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2−
✍ Minoru Nakano; Katsuaki Sugioka; Yoshio Ushijima; Toshio Goto 📂 Article 📅 1986 🏛 Elsevier Science 🌐 English ⚖ 519 KB

The Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one (CLA), in Hanks' balanced salt solution, emitted a weak luminescence which was not affected by superoxide dismutase or catalase and was not augmented by resting human granulocytes. In contrast, activated granulo