The development and validation of a comp
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Cheng Chang; David B. Duignan; Kjell D. Johnson; Pil H. Lee; George S. Cowan; Er
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Article
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2009
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John Wiley and Sons
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English
โ 227 KB
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As the cost of discovering and developing new pharmaceutically relevant compounds continues to rise, it is increasingly important to select the right molecules to prosecute very early in drug discovery. The development of high throughput in vitro assays of hepatic metabolic clearance has allowed for