A semi-automated system for quantitative densitometry of autoradiographs
β Scribed by Timothy T. Soncrant
- Book ID
- 103051304
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 847 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0010-4825
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β¦ Synopsis
We describe a semi-automatic, computerized method of quantitative densitometry for regional analysis of whole brain autoradiographs. The technique features menu-driven software and verbal prompting for data via a speech synthesizer. Advantages over manual methods include an 80% reduction in the time required for data collection, easy retrieval and statistical analysis of data, and the production of a large data base for future use. The application of this system to the [14C]2-deoxy-D-glucose autoradiographic method for measurement of local cerebral glucose utilization is described. This system makes available computerized densitometry at a modest cost.
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