A self-Ia reactive T cell clone directly stimulates every hundredth B cell and helps antigen-specific B cell responses

Antigen-specific major histocompatibilit

Antigen-specific major histocompatibility complex-restricted helper T cell clones are sufficient to induce unprimed B cells to switch and to secrete IgG and IgA in a primary in vitro polyclonal response

✍ Lise Leclercq; Patricia Chastagnier; Zohair Mishal; Georges Bismuth; Jacques Thè 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 828 KB

## Antigen-specific major histocompatibility complexrestricted helper T cell clones are sufficient to induce unprimed B cells to switch and to secrete IgG and IgA in a primary in vitro polyclonal response To investigate the role of helper T (Th) cells in the regulation of the production of the var