The E isomer of (123)I-2beta-carbomethoxy-3beta-(4-fluorophenyl)-N-(1-iodoprop-1-en-3-yl)nortropane (Altropane(R)) shows high affinity (IC(50) = 6.62 +/- 0.78 nmol) and selectivity (DA/5-HT = 25) for DAT sites in the striatum. Recently, dynamic SPECT studies in healthy volunteers and patients with P
✦ LIBER ✦
A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: Pharmacological evaluation and pet experiments
✍ Scribed by J. Helfenbein; C. Loc'h; M. Bottlaender; P. Emond; C. Coulon; M Ottaviani; C. Fuseau; S. Chalon; I. Guenther; J-C. Besnard; Y. Frangin; D. Guilloteau; B. Maziere
- Book ID
- 117176582
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 857 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0024-3205
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