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A selective method for studying primary sex chromosome non-disjunction in females and males and X-Y exchange in males ofDrosophila melanogasterincluding a demonstration of euchromatic X-Y exchange

✍ Scribed by P. Portin; M. Rantanen


Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
353 KB
Volume
85
Category
Article
ISSN
0016-6707

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✦ Synopsis


A selective method was developed, based on negative complementation of the Abruptex alleles of the Notch locus, for studying primary sex chromosome non-disjunction in females and males of Drosophila melanogaster and X-Y exchange in males. The results show that the frequency of primary non-disjunction of structurally normal X chromosomes was lower than the frequency of X-derY non-disjunction in males. Double exchange between the X and the derY chromosome in the male occurs with a frequency of at least 0.091%. Single exchanges are naturally expected to occur with even higher frequency. Exchanges were interestingly at least partly of euchromatic nature. The origin of these exchanges is at least partly of gonial origin.