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A Selective Inhibitor of eIF2 Dephosphorylation Protects Cells from ER Stress

โœ Scribed by Boyce, M.


Book ID
111910916
Publisher
American Association for the Advancement of Science
Year
2005
Tongue
English
Weight
522 KB
Volume
307
Category
Article
ISSN
0036-8075

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## Abstract Chronic exposure to elevated concentration of free fatty acids (FFA) has been verified to induce endoplasmic reticulum (ER) stress, which leads to pancreatic ฮฒโ€cell apoptosis. As one of the medium and long chain FFA receptors, GPR40 is highly expressed in pancreatic ฮฒ cells, mediates bo