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A Selective Direct Aldol Reaction in Aqueous Media Catalyzed byZinc–Proline

✍ Scribed by Ruben Fernandez-Lopez; Jacob Kofoed; Miguel Machuqueiro; Tamis Darbre

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
158 KB
Volume
2005
Category
Article
ISSN
1434-193X

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A Selective Direct Aldol Reaction in Aqu
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## Abstract The direct aldol reaction of 4‐nitrobenzaldehyde catalyzed by NaHCO~3~, with three different ketones, Znproline, NaHCO~3~/Znproline, and L‐proline/Znproline in aqueous media, was studied to explore the selectivity of this environmentally benign type of reaction. Amazingly, NaHCO~3~ p