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A Second Right-handed Helical Structure with the Parameters of the Pauling–Corey α-helix

✍ Scribed by NÉMETHY, GEORGE; PHILLIPS, D. C.; LEACH, S. J.; SCHERAGA, HAROLD A.


Book ID
109656599
Publisher
Nature Publishing Group
Year
1967
Tongue
English
Weight
321 KB
Volume
214
Category
Article
ISSN
0028-0836

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## Abstract The 173–195 segment corresponding to the helix 2 of the globular PrP domain is a good candidate to be one of the several ‘spots’ of intrinsic structural flexibility, which might induce local destabilization and concur to protein transformation, leading to aggregation‐prone conformations