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A Second Genetic Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Associated with Decreased Enzyme Activity

✍ Scribed by Ilan Weisberg; Pamela Tran; Benedicte Christensen; Sahar Sibani; Rima Rozen

Book ID: 115639404
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 60 KB
Volume: 64
Category: Article
ISSN: 1096-7192
DOI: 10.1006/mgme.1998.2714

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## Abstract ## BACKGROUND The importance of metabolic factors in neural tube defects (NTDs) has been the focus of many investigations. Several authors have suggested that abnormalities in homocysteine metabolism, such as hyperhomocysteinemia, folate deficiency, and low vitamin B12, may be responsi