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A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

✍ Scribed by Koo, Edward H.; Bredesen, Dale E.; Lu, Daniel C.; Rabizadeh, Shahrooz; Chandra, Sreeganga; Shayya, Rana F.; Ellerby, Lisa M.; Ye, Xin; Salvesen, Guy S.


Book ID
109828034
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
441 KB
Volume
6
Category
Article
ISSN
1078-8956

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## ABSTRACT Antimicrobial peptides are important effector molecules of the innate immune system. Here, we describe that peptides derived from the heparin‐binding disulfide‐constrained loop region of human __ß__‐amyloid precursor protein are antimicrobial. The peptides investigated were linear and c