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A search for an intermediate in carboxypeptidase A catalyzed ester hydrolyses

✍ Scribed by Tomalin, Geoffrey.; Kaiser, B. L.; Kaiser, Emil T.

Book ID
126249806
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
497 KB
Volume
92
Category
Article
ISSN
0002-7863

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πŸ“œ SIMILAR VOLUMES

Carboxypeptidase A-Catalyzed Hydrolysis
Carboxypeptidase A-Catalyzed Hydrolysis of O-(Ξ±-Acylamino-2-Styrylacryloyl)-L-Ξ²-Phenyllactates: Search of Specific Ester Substrates Hydrolyzed through Accumulation of Intermediates
✍ S. Lee; B.K. Hwang; Y.C. Myoung; J.H. Suh πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 420 KB

Results of a previous study on the hydrolysis of \(O\)-( \(\alpha\)-acylamino-cinnamoyl)-L- \(\beta\)-phenyllactates \(E 1\) and \(\mathbf{E} 2\) catalyzed by carboxypeptidase \(A(C P A)\) supported the anhydride mechanism for the action of CPA. Since these esters are hydrolyzed very slowly by CPA,