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A Screening System for Enantioselective Enzymes Based on Differential Cell Growth.

✍ Scribed by Manfred T. Reetz; Carsten J. Rueggeberg


Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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An efficient enzyme model exhibiting enantioselective esterase activity was prepared by using molecular imprinting techniques. The enantiomerically pure phosphonic monoesters 4 L and 5 L were synthesized as stable transition-state analogues. They were used as templates connected by stoichiometric no