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A score test for the linkage analysis of qualitative and quantitative traits based on identity [...]

✍ Scribed by Dudoit S., Speed T. P.

Book ID
127406035
Tongue
English
Weight
768 KB
Category
Library

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πŸ“œ SIMILAR VOLUMES

Power and robustness of a score test for
Power and robustness of a score test for linkage analysis of quantitative traits using identity by descent data on sib pairs
✍ Darlene R. Goldstein; Sandrine Dudoit; Terence P. Speed πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 137 KB πŸ‘ 2 views

## Abstract Identification of genes involved in complex traits by traditional (lod score) linkage analysis is difficult due to many complicating factors. An unfortunate drawback of non‐parametric procedures in general, though, is their low power to detect genetic effects. Recently, Dudoit and Speed

Robust genetic linkage analysis based on
Robust genetic linkage analysis based on a score test of homogeneity: The weighted pairwise correlation statistic
✍ D. Commenges πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 589 KB

## Abstract In testing genetic linkage using large or complex pedigrees, robust methods may be preferred to the Lod‐score method. The affected‐pedigree‐member method is robust but does not use the information available in nonaffected subjects, which results in a loss of power. We propose a new test